Binary or ternary mixture of solid dispersion: Meloxicam case

The present work was carried out to assess the value of adding water insoluble polymer meloxicam amorphous solid formulation (ASD). Meloxicam mixed with polyvinylpyrrolidone (PVP) (1:1 ratio) as a binary mixture and PVP ethyl cellulose (1:1:1 ternary mixture. Solvent evaporation method used prepare ASD formulations. differential scanning calorimetry, powder X-Ray diffraction, Cambridge Structural Database in-vitro dissolution were performed formulas. results showed that addition could prevent recrystallization process during formation. However, higher drug release percentage than Therefore, rational amount be considered control manipulate from